Purnima Sinha studied physics at the University of Calcutta in the late 1940s. During her time as an undergraduate, she was taught by Satyendra Nath Bose, who encouraged her to join his research group and undertake a PhD in X-ray spectroscopy. Sinha became the first Bengali women to receive a doctorate in physics in 1956. The PhD students worked together to collect scrap army surplus equipment which was readily available after the second world war to build equipment for their research. Sinha studied the structure of clay; later, she joined a biophysics department at Stanford University and found structural similarities between the geometries of clay and of DNA.
In addition, to her scientific pursuits, Sinha was an accomplished musician, painter and translated many science books into Bengali. In 1970, she published an anthropology book on Indian folk music. Sinha was actively involved in Bengali Science Association, which had been set up by Bose. After retirement, she also created an informal school for children of ethnic minorities.
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